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"I wish that there was more info": characterizing the uncertainty experienced by carriers of pathogenic ATM and/or CHEK2 variants.

Familial cancer - 1 Apr 2022

Reyes Kathryn G, Clark Cheyla, Gerhart Meredith, Newson Ainsley J, Ormond Kelly E

Abstract excerpt

Little is known about what uncertainties patients experience after being identified to carry a pathogenic variant in a moderate-risk cancer gene as a result of undergoing multigene panel testing for cancer susceptibility. Data regarding cancer risk estimates and effectiveness of risk management strategies for these variants continues to evolve, which has the potential to evoke uncertainty. Acknowledging...

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PMID: 33855648
DOI: 10.1007/s10689-021-00251-3

Genes

ATM
CHEK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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