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Malignant Proliferating Pilar Tumor: Clinicopathologic, Immunohistochemical, and Molecular Study of 17 Cases.

The American journal of surgical pathology - 1 Oct 2023

Moran Jakob M T, DeSimone Mia S, Mariño-Enríquez Adrián, Russell-Goldman Eleanor E, Fletcher Christopher D M, Mochel Mark C, Hoang Mai P

Abstract excerpt

Proliferating pilar tumors are rare neoplasms that differentiate toward the outer sheath near the isthmus and can rarely undergo malignant transformation. We performed histopathologic evaluation on 26 benign proliferating pilar tumor (BPPT) and 17 malignant proliferating pilar tumor (MPPT). Ki-67 and p53 immunostains were performed on 13 BPPT and 10 MPPT. Six MPPT cases were successfully analyzed by a...

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Biomarkers, Tumor
Carcinoma, Squamous Cell
Mutation
Necrosis
Precancerous Conditions

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PMID: 37515420
DOI: 10.1097/PAS.0000000000002105

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