KRAS codon 12 mutations characterize a subset of de novo proliferating "metaplastic" Warthin tumors.

doi:10.1007/s00428-023-03504-x

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Article

KRAS codon 12 mutations characterize a subset of de novo proliferating "metaplastic" Warthin tumors.

Virchows Archiv : an international journal of pathology - 1 May 2023

Agaimy Abbas, Mantsopoulos Konstantinos, Iro Heinrich, Stoehr Robert

Abstract excerpt

Warthin tumor (WT; synonym: cystadenolymphoma) represents one of the most frequent salivary gland tumors with a frequency equaling or even outnumbering that of pleomorphic adenomas in some series. Histologically, the tumor displays tall columnar oncocytic cells, arranged into two cell-thick layers lining variably cystic glands within an organoid lymphoid stroma. Tumors with exuberant squamous metaplasia in...

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PMID: 36752878
DOI: 10.1007/s00428-023-03504-x
PMCID: PMC10156774

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