Article
Genetic Ancestry Estimates within Dutch Family Units and Across Genotyping Arrays: Insights from Empirical Analysis Using Two Estimation Methods.
Genes - 22 Jul 2023
Beck Jeffrey J, Ahmed Talitha, Finnicum Casey T, Zwinderman Koos, Ehli Erik A, Boomsma Dorret I, Hottenga Jouke Jan
Abstract excerpt
Accurate inference of genetic ancestry is crucial for population-based association studies, accounting for population heterogeneity and structure. This study analyzes genome-wide SNP data from the Netherlands Twin Register to compare genetic ancestry estimates. The focus is on the comparison of ancestry estimates between family members and individuals genotyped on multiple arrays (Affymetrix 6.0, Affymetrix...
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