Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Metallodrug BOLD-100 Is a Potent Inhibitor of SARS-CoV-2 Replication and Has Broad-Acting Antiviral Activity

8 Jul 2023

Abstract excerpt

The COVID-19 pandemic has highlighted an urgent need to discover and test new drugs to treat patients. Metal-based drugs are known to interact with DNA and/or a variety of proteins such as enzymes and transcription factors, some of which have been shown to exhibit anticancer and antimicrobial effects. BOLD-100 (sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)]dihydrate) is a novel ruthenium-based drug...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37509131
DOI: 10.3390/biom13071095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Metallodrug BOLD-100 Is a Potent Inhibitor of SARS-CoV-2 Replication and Has Broad-Acting Antiviral ActivityPMID 37509131Read ↗

Metallodrugs: an approach against invasion and metastasis in cancer treatmentSemantic proximity Read ↗

Metal Complexes as DNA Synthesis and/or Repair Inhibitors: Anticancer and Antimicrobial AgentsSemantic proximity Read ↗

Heterocyclic Schiff base transition metal complexes in antimicrobial and anticancer chemotherapySemantic proximity Read ↗

Metal-based anticancer drugs: From a past anchored in platinum chemistry to a post-genomic future of diverse chemistry and biologySemantic proximity Read ↗

Exploring Anticancer and Antituberculosis Activities of Pt(II) Quinazoline Complexes Derived from EMNEDAQZHO ((E)-2-methyl-3-(1-(naphthalen-1-yl)ethylideneamino)quinazolin-4(3H)-one): Insights and ApplicationsSemantic proximity Read ↗

Anti-COVID-19 Activity of FDA Approved Drugs through RNA G-quadruplex BindingSemantic proximity Read ↗

Anthracyclines inhibit SARS-CoV-2 infectionSemantic proximity Read ↗

Utilization of Cancer Cell Line Screening to Elucidate the Anticancer Activity and Biological Pathways Related to the Ruthenium-Based Therapeutic BOLD-100Semantic proximity Read ↗

Exploring Titanium(IV) Complexes as Potential Antimicrobial CompoundsSemantic proximity Read ↗

Zinc <sup>2+</sup> ion inhibits SARS-CoV-2 main protease and viral replication <i>in vitro</i>Semantic proximity Read ↗

Progress of Metal‐Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding, Cleavage and Cytotoxicity Activity) StudiesSemantic proximity Read ↗

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.