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Article

Molecular and haematological characterisation of haemolytic anaemia associated with biallelic KLF1 mutations: a case series.

Journal of clinical pathology - 20 Oct 2024

Singha Kritsada, Teawtrakul Nattiya, Fucharoen Goonnapa, Fucharoen Supan

Abstract excerpt

AIMS: Krüppel-like factor 1 (KLF1) is an erythroid-specific transcription factor playing an important role in erythropoiesis and haemoglobin (Hb) switching. Biallelic KLF1 mutations can cause haemolytic anaemia with thalassaemia-like syndromes but are rarely reported. We explore the KLF1 mutations in Thai subjects with unexplainable haemolytic anaemia. METHODS: The study was done on 57 subjects presented with...

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Identifiers

PMID: 37507221
DOI: 10.1136/jcp-2023-208945

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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