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Pluripotent Stem Cell-Derived In Vitro Gametogenesis and Synthetic Embryos—It Is Never Too Early for an Ethical Debate

20 Jul 2023

Abstract excerpt

Recently, 2 branches of the wide area of synthetic biology-in vitro gametogenesis and synthetic embryo development-have gained considerable attention. Rodent induced pluripotent stem cells derived via reprogramming of somatic cells can in vitro be differentiated into gametes to produce fertile offspring. And even synthetic embryos with organ progenitors were generated ex utero entirely from murine pluripotent...

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PMID: 37471266
DOI: 10.1093/stcltm/szad042

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