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Article

Spatial clustering of amyotrophic lateral sclerosis in Sardinia, Italy: The contribution of age, sex, and genetic factors.

Muscle & nerve - 1 Sept 2023

Borghero Giuseppe, Sechi Maria Margherita, Vasta Rosario, Pierri Vincenzo, Pili Francesca, Pateri Ida, Pilotto Silvy, Ercoli Tommaso, Muroni Antonella, Chiò Adriano, Defazio Giovanni

Abstract excerpt

INTRODUCTION/AIMS: Several microgeographic clusters of higher/lower incidence of amyotrophic lateral sclerosis (ALS) have been identified worldwide. Differences in the distribution of local factors were proposed to explain the excess ALS risk, whereas the contribution of known genetic/epigenetic factors remains unclear. The aim is to identify restricted areas of higher risk in Sardinia and to assess whether age,...

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PMID: 37466098
DOI: 10.1002/mus.27939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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