Article
Clinical and demographic factors and outcome of amyotrophic lateral sclerosis in relation to population ancestral origin.
European journal of epidemiology - 1 Mar 2016
Marin Benoît, Logroscino Giancarlo, Boumédiene Farid, Labrunie Anaïs, Couratier Philippe, Babron Marie-Claude, Leutenegger Anne Louise, Preux Pierre Marie, Beghi Ettore
Abstract excerpt
BACKGROUND: To review how the phenotype and outcome of amyotrophic lateral sclerosis (ALS) change with variations in population ancestral origin (PAO). Knowledge of how PAO modifies ALS phenotype may provide important insight into the risk factors and pathogenic mechanisms of the disease. METHODS: We performed a systematic review and meta-analysis of the literature concerning differences in phenotype and outcome...
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