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Article

DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex

18 Jul 2023

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Share to interferon and immune responses
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Share to Viral Infections and Vectors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37462751
DOI: 10.1007/s00018-023-04860-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complexPMID 37462751Read ↗

Zika virus NS5 protein antagonizes type I interferon production via blocking TBK1 activationSemantic proximity Read ↗

DDX6 is involved in the pathogenesis of inflammatory diseases via NF-κB activationSemantic proximity Read ↗

STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediationSemantic proximity Read ↗

The DEAD‐box helicase DDX3X is a critical component of the TANK‐binding kinase 1‐dependent innate immune responseSemantic proximity Read ↗

DDX50 is a viral restriction factor that enhances TRIF-dependent IRF3 activationSemantic proximity Read ↗

The DEAD-box RNA helicase DDX5 acts as a positive regulator of Japanese encephalitis virus replication by binding to viral 3′ UTRSemantic proximity Read ↗

Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genesSemantic proximity Read ↗

DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infectionSemantic proximity Read ↗

TRIM28 facilitates type I interferon activation by targeting TBK1Semantic proximity Read ↗

The DEAD-Box RNA Helicase DDX1 Interacts with the Viral Protein 3D and Inhibits Foot-and-Mouth Disease Virus ReplicationSemantic proximity Read ↗

DDX50 Is a Viral Restriction Factor That Enhances IRF3 ActivationSemantic proximity Read ↗

Tick-borne encephalitis virus NS4A ubiquitination antagonizes type I interferon-stimulated STAT1/2 signalling pathwaySemantic proximity Read ↗

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