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Distinct hepatocyte identities in liver homeostasis and regeneration

24 Apr 2023

Abstract excerpt

The process of metabolic liver zonation is spontaneously established by assigning distributed tasks to hepatocytes along the porto-central blood flow. Hepatocytes fulfil critical metabolic functions, while also maintaining hepatocyte mass by replication when needed. Recent technological advances have enabled us to fine-tune our understanding of hepatocyte identity during homeostasis and regeneration. Subsets of...

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PMID: 37456678
DOI: 10.1016/j.jhepr.2023.100779

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