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Article

Individualized dynamic methylation-based analysis of cell-free DNA in postoperative monitoring of lung cancer

14 Jul 2023

Abstract excerpt

BACKGROUND: The feasibility of DNA methylation-based assays in detecting minimal residual disease (MRD) and postoperative monitoring remains unestablished. We aim to investigate the dynamic characteristics of cancer-related methylation signals and the feasibility of methylation-based MRD detection in surgical lung cancer patients. METHODS: Matched tumor, tumor-adjacent tissues, and longitudinal blood samples from...

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PMID: 37452374
DOI: 10.1186/s12916-023-02954-z

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