Article
TRIM21 Promotes Rabies Virus Production by Degrading IRF7 through Ubiquitination
30 Jun 2023
Abstract excerpt
Rabies, a highly fatal zoonotic disease, is a significant global public health threat. Currently, the pathogenic mechanism of rabies has not been fully elucidated, and no effective treatment for rabies is available. Increasing evidence shows that the tripartite-motif protein (TRIM) family of proteins participates in the host's regulation of viral replication. Studies have demonstrated the upregulated expression...
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