Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trim25 restricts rabies virus replication by destabilizing phosphoprotein

29 Sept 2022

Abstract excerpt

Tripartite motif-containing protein 25 (Trim25) is an E3 ubiquitin ligase that activates retinoid acid-inducible gene I (RIG-I) and promotes the antiviral interferon response. Recent studies have shown that Trim25 can bind and degrade viral proteins, suggesting a different mechanism of Trim25 on its antiviral effects. In this study, Trim25 expression was upregulated in cells and mouse brains after rabies virus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Rabies epidemiology and control
Share to Toxoplasma gondii Research Studies
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37193556
DOI: 10.1016/j.cellin.2022.100057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trim25 restricts rabies virus replication by destabilizing phosphoproteinPMID 37193556Read ↗

TRIM21 Promotes Rabies Virus Production by Degrading IRF7 through UbiquitinationSemantic proximity Read ↗

TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix proteinSemantic proximity Read ↗

The Function of TRIM25 in Antiviral Defense and Viral Immune EvasionSemantic proximity Read ↗

TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix proteinSemantic proximity Read ↗

TRIM Proteins and Their Roles in Antiviral Host DefensesSemantic proximity Read ↗

The E3 Ubiquitin Ligase TRIM25 Inhibits Tembusu Virus Replication in vitroSemantic proximity Read ↗

Zebrafish TRIM2a promotes virus replication via ubiquitination of IRF3 and autophagic cargo receptor p62Semantic proximity Read ↗

MiR-202-5p Inhibits RIG-I-Dependent Innate Immune Responses to RGNNV Infection by Targeting TRIM25 to Mediate RIG-I UbiquitinationSemantic proximity Read ↗

TRIM52 inhibits Japanese Encephalitis Virus replication by degrading the viral NS2ASemantic proximity Read ↗

TRIM22: A Diverse and Dynamic Antiviral ProteinSemantic proximity Read ↗

Middle East Respiratory Syndrome Coronavirus Nucleocapsid Protein Suppresses Type I and Type III Interferon Induction by Targeting RIG-I SignalingSemantic proximity Read ↗

TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.