Article
SARS-CoV-2 evolution in the Omicron era.
Nature microbiology - 1 Nov 2023
Roemer Cornelius, Sheward Daniel J, Hisner Ryan, Gueli Federico, Sakaguchi Hitoshi, Frohberg Nicholas, Schoenmakers Josette, Sato Kenta, O'Toole Áine, Rambaut Andrew, Pybus Oliver G, Ruis Christopher, Murrell Ben, Peacock Thomas P
Abstract excerpt
Since SARS-CoV-2 BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have markedly diversified. Here we review the evolutionary trajectories and processes that underpin the emergence of these lineages, and identify the most prevalent sublineages. We discuss the potential origins of second-generation BA.2 lineages. Simple and complex recombination, antigenic drift and convergent evolution have enabled...
Topics
- Humans
- COVID-19
- SARS-CoV-2
- Mutation
