Article
Characterizations of SARS-CoV-2 mutational profile, spike protein stability and viral transmission.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020
Laha Sayantan, Chakraborty Joyeeta, Das Shantanab, Manna Soumen Kanti, Biswas Sampa, Chatterjee Raghunath
Abstract excerpt
The recent pandemic of SARS-CoV-2 infection has affected more than 3.0 million people worldwide with more than 200 thousand reported deaths. The SARS-CoV-2 genome has the capability of gaining rapid mutations as the virus spreads. Whole-genome sequencing data offers a wide range of opportunities to study mutation dynamics. The advantage of an increasing amount of whole-genome sequence data of SARS-CoV-2 intrigued...
Topics
- Humans
- Models, Molecular
- Mutation
- Phylogeny
- Protein Conformation
- Protein Domains
- SARS-CoV-2
- Sequence Alignment
- Spike Glycoprotein, Coronavirus
- Whole Genome Sequencing