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Empirically derived sequence similarity thresholds to study the genomic epidemiology of plasmids shared among healthcare-associated bacterial pathogens

29 Jun 2023

Abstract excerpt

BACKGROUND: Healthcare-associated bacterial pathogens frequently carry plasmids that contribute to antibiotic resistance and virulence. The horizontal transfer of plasmids in healthcare settings has been previously documented, but genomic and epidemiologic methods to study this phenomenon remain underdeveloped. The objectives of this study were to apply whole-genome sequencing to systematically resolve and track...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37392596
DOI: 10.1016/j.ebiom.2023.104681

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