Article
Ultrasensitive and Specific Clustered Regularly Interspaced Short Palindromic Repeats Empowered a Plasmonic Fiber Tip System for Amplification-Free Monkeypox Virus Detection and Genotyping.
ACS nano - 11 Jul 2023
Chen Yuzhi, Chen Zhi, Li Tianzhong, Qiu Meng, Zhang Jinghan, Wang Yan, Yuan Wu, Ho Aaron Ho-Pui, Al-Hartomy Omar, Wageh Swelm, Al-Sehemi Abdullah G, Shi Xin, Li Jingfeng, Xie Zhongjian, Xuejin Li, Zhang Han
Abstract excerpt
The urgent necessity for highly sensitive diagnostic tools has been accentuated by the ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying asymptomatic and presymptomatic carriers. Traditional polymerase chain reaction-based tests, despite their effectiveness, are hampered by limited specificity, expensive and bulky equipment, labor-intensive operations, and time-consuming procedures. In...
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