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Development of a CRISPR/Cas12a-mediated aptasensor for Mpox virus antigen detection

24 Apr 2024

Abstract excerpt

The emergence and rapid spread of Mpox (formerly monkeypox) have caused significant societal challenges. Adequate and appropriate diagnostics procedures are an urgent necessity. Herein, we discover a pair of aptamers through the systematic evolution of ligands by exponential enrichment (SELEX) that exhibit high affinity and bind to different sites towards the A29 protein of the Mpox virus . Subsequently, we...

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PMID: 38688229
DOI: 10.1016/j.bios.2024.116313

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