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Clinical outcome of pediatric medulloblastoma patients with Li–Fraumeni syndrome

28 Jun 2023

Abstract excerpt

BACKGROUND: The prognosis for Li-Fraumeni syndrome (LFS) patients with medulloblastoma (MB) is poor. Comprehensive clinical data for this patient group is lacking, challenging the development of novel therapeutic strategies. Here, we present clinical and molecular data on a retrospective cohort of pediatric LFS MB patients. METHODS: In this multinational, multicenter retrospective cohort study, LFS patients under...

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PMID: 37379234
DOI: 10.1093/neuonc/noad114

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