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Article

Single-Droplet Microsensor for Ultra-Short Circulating EFGR Mutation Detection in Lung Cancer Based on Multiplex EFIRM Liquid Biopsy.

International journal of molecular sciences - 20 Jun 2023

Wei Fang, Yu Peter, Cheng Jordan, Li Feng, Chia David, Wong David T W

Abstract excerpt

Liquid biopsy is a rapidly emerging field that involves the minimal/non-invasive assessment of signature somatic mutations through the analysis of circulating tumor DNA (ctDNA) shed by tumor cells in bodily fluids. Broadly speaking, the unmet need in liquid biopsy lung cancer detection is the lack of a multiplex platform that can detect a mutation panel of lung cancer genes using a minimum amount of sample,...

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PMID: 37373532
DOI: 10.3390/ijms241210387
PMCID: PMC10299723

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