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Article

The rs16969968 Tobacco Smoking-Related Single-Nucleotide Variant Is Associated with Clinical Markers in Patients with Severe COVID-19.

International journal of molecular sciences - 6 Jun 2023

Valencia-Pérez Rea Daniela, Falfán-Valencia Ramcés, Fricke-Galindo Ingrid, Buendía-Roldán Ivette, Chávez-Galán Leslie, Nava-Quiroz Karol J, Alanis-Ponce Jesús, Pérez-Rubio Gloria

Abstract excerpt

Tobacco smoking is the leading risk factor for many respiratory diseases. Several genes are associated with nicotine addiction, such as CHRNA5 and ADAM33. This research aims to evaluate the association of the polymorphisms rs16969968 (CHRNA5) and rs3918396 (ADAM33) in patients who developed severe COVID-19. We included 917 COVID-19 patients hospitalized with critical disease and oxygenation impairment. They were...

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Identifiers

PMID: 37372959
DOI: 10.3390/ijms24129811
PMCID: PMC10298344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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