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CFAP70 is a solid and valuable target for the genetic diagnosis of oligo-astheno-teratozoospermia in infertile men

21 Jun 2023

Abstract excerpt

BACKGROUND: Male infertility is a worldwide population health concern, but its aetiology remains largely understood. Although CFAP70 variants have already been reported in two oligo-astheno-teratozoospermia (OAT) individuals by sequencing, animal evidence to support CFAP70 as a credible OAT-pathogenic gene is lacking. METHOD: Cfap70-KO mice were generated to explore the physiological role of CFAP70. CFAP70...

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PMID: 37352829
DOI: 10.1016/j.ebiom.2023.104675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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