Article
Pathological criteria for multiplex gene-panel testing using next-generation sequencing in non-small cell lung cancer.
Cancer treatment and research communications - 1 Jan 2022
Mizote Shihoko, Matsumura Mai, Sekiya Motoki, Sugiyama Misaki, Sekine Akimasa, Kobayashi Nobuaki, Kataoka Toshiaki, Iwashita Hiromichi, Okudela Koji
Abstract excerpt
BACKGROUND: Multiplex gene-panel tests have recently been developed, including the Oncomine Dx Target Test multi-CDx system (ODxTT), and are commonly used to determine the adaptation of molecular-targeting drugs in non-small cell lung cancer. However, in actual clinical settings, we obtain false results owing to the small biopsy samples. We aimed to optimize tissue preparation methods to improve the success rate....
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