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Article

The underlying mechanism of transcription factor IRF1, PRDM1, and ZNF263 involved in the regulation of NPPB rs3753581 on pulse pressure hypertension.

Gene - 20 Aug 2023

Wu Xiaodan, Zhang Na, Yu Jianjun, Liang Min, Xu Haojie, Hu Jiamin, Lin Shizhu, Qiu Jingjia, Lin Caizhu, Liu Weilin, Chai Dajun, Zeng Kai

Abstract excerpt

To investigate the correlation between NPPB gene variants and pulse pressure hypertension and the underlying regulatory mechanisms and try to confirm that NPPB may be a potential molecular target of gene therapy for pulse pressure hypertension. A total of 898 participants were recruited from the First Affiliated Hospital of Fujian Medical University and the plasmids with differential expression of NPPB were...

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Identifiers

PMID: 37339722
DOI: 10.1016/j.gene.2023.147580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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