Article
STMN-1 is a potential marker of lymph node metastasis in distal esophageal adenocarcinomas and silencing its expression can reverse malignant phenotype of tumor cells.
BMC cancer - 16 Jan 2014
Akhtar Javed, Wang Zhou, Yu Che, Li Chen-Sheng, Shi Yu-Long, Liu Hong-Jun
Abstract excerpt
BACKGROUND: Distal esophageal adenocarcinoma is a highly aggressive neoplasm. Despite advances in diagnosis and therapy, the prognosis is still poor. Stathmin (STMN-1) is a ubiquitously expressed microtubule destabilizing phosphoprotein. It promotes the disassembly of microtubules and prevents as...
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