Article
Proton and alpha radiation-induced mutational profiles in human cells.
Scientific reports - 16 Jun 2023
Delhomme Tiffany M, Munteanu Maia, Buonanno Manuela, Grilj Veljko, Biayna Josep, Supek Fran
Abstract excerpt
Ionizing radiation is known to be DNA damaging and mutagenic, however less is known about which mutational footprints result from exposures of human cells to different types of radiation. We were interested in the mutagenic effects of particle radiation exposures on genomes of various human cell types, in order to gauge the genotoxic risks of galactic cosmic radiation, and of certain types of tumor radiotherapy....
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