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Article

REM-related obstructive sleep apnea: low AHI-high hypoxemia paradox.

Sleep & breathing = Schlaf & Atmung - 24 Nov 2025

Verdi Elvan Burak, Acıcan Turan

Abstract excerpt

PURPOSE: REM-related obstructive sleep apnea (OSA) presents a paradox where a low apnea-hypopnea index (AHI) may mask significant disease. We compared polysomnography, comorbidities, and oxygenation metrics across OSA phenotypes to determine if AHI-based severity classifications underestimate the...

Topics

Humans
Sleep Apnea, Obstructive
Male
Female
Hypoxia
Polysomnography
Middle Aged
Retrospective Studies
Sleep, REM
Adult
Aged
Comorbidity
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxygen Saturation

Source

Identifiers

PMID: 41284107
DOI: 10.1007/s11325-025-03551-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-41284107-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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