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Article

Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers.

Journal of neuro-oncology - 1 Jun 2023

Khan A Basit, Patel Rajan, McDonald Malcolm F, Goethe Eric, English Collin, Gadot Ron, Shetty Arya, Nouri Shervin Hosseingholi, Harmanci Arif O, Harmanci Akdes S, Klisch Tiemo J, Patel Akash J

Abstract excerpt

INTRODUCTION: Meningiomas are the most common primary intracranial tumor. Recently, various genetic classification systems for meningioma have been described. We sought to identify clinical drivers of different molecular changes in meningioma. As such, clinical and genomic consequences of smoking in patients with meningiomas remain unexplored. METHODS: 88 tumor samples were analyzed in this study. Whole exome...

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PMID: 37318677
DOI: 10.1007/s11060-023-04359-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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