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Article

A Clinical Diagnosis of Laminopathy without Systolic Dysfunction: When Does Nuclei Malformation Start?

Internal medicine (Tokyo, Japan) - 1 Feb 2024

Kataoka Naoya, Imamura Teruhiko, Nakamura Makiko, Kinugawa Koichiro

Abstract excerpt

Nuclear shape abnormalities in laminopathy are well known to occur in patients with cardiac systolic dysfunction. However, those in patients without systolic dysfunction are still unclear. We herein report a 42-year-old man who presented with advanced atrioventricular block without systolic dysfunction. Genetic testing identified a laminopathic mutation, c.497G>C, and an endocardial biopsy was performed. The...

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Identifiers

PMID: 37316273
DOI: 10.2169/internalmedicine.1928-23
PMCID: PMC10901699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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