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Article

Cross-talk between CFTR and sphingolipids in cystic fibrosis.

FEBS open bio - 1 Sept 2023

Dobi Dorina, Loberto Nicoletta, Bassi Rosaria, Pistocchi Anna, Lunghi Giulia, Tamanini Anna, Aureli Massimo

Abstract excerpt

Cystic fibrosis (CF) is the most common inherited, life-limiting disorder in Caucasian populations. It is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), which lead to an impairment of protein expression and/or function. CFTR is a chloride/bicarbonate channel expressed at the apical surface of epithelial cells of different organs. Nowadays, more than 2100...

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Identifiers

PMID: 37315117
DOI: 10.1002/2211-5463.13660
PMCID: PMC10476574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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