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Synthase-selected sorting approach identifies a beta-lactone synthase in a nudibranch symbiotic bacterium

13 Jun 2023

Abstract excerpt

BACKGROUND: Nudibranchs comprise a group of > 6000 marine soft-bodied mollusk species known to use secondary metabolites (natural products) for chemical defense. The full diversity of these metabolites and whether symbiotic microbes are responsible for their synthesis remains unexplored. Another issue in searching for undiscovered natural products is that computational analysis of genomes of uncultured microbes...

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PMID: 37312139
DOI: 10.1186/s40168-023-01560-8

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