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Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in TropicalDysideidaeSponges

13 May 2019

Abstract excerpt

Natural products provide the inspiration for most clinical drugs. With the rise in antibiotic resistance, it is imperative to discover new sources of chemical diversity. Bacteria living in symbiosis with marine invertebrates have emerged as an untapped source of natural chemistry. While symbiotic bacteria are often recalcitrant to growth in the lab, advances in metagenomic sequencing and assembly now make it...

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PMID: 31088928
DOI: 10.1128/mbio.00821-19

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