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Chain hybridization-based CRISPR-lateral flow assay enables accurate gene visual detection.

Analytica chimica acta - 22 Aug 2023

Cheng Meng, Tan Caiwei, Xiang Bo, Lin Weihong, Cheng Bolin, Peng Xuechun, Yang Yihao, Lin Yongping

Abstract excerpt

Visualized gene detection based on the CRISPR-Cas12/CRISPR-Cas13 technology and lateral flow assay device (CRISPR-LFA) has shown great potential in point-of-care testing sector. Current CRISPR-LFA methodology mainly utilizes conventional immuno-based LFA test strips, which could visualize whether the reporter probe is trans-cleaved by Cas protein, indicating the target positive detection. However, conventional...

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PMID: 37311609
DOI: 10.1016/j.aca.2023.341437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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