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Article

Functional CVIDs phenotype clusters identified by the integration of immune parameters after BNT162b2 boosters.

Frontiers in immunology - 1 Jan 2023

Piano Mortari Eva, Pulvirenti Federica, Marcellini Valentina, Terreri Sara, Salinas Ane Fernandez, Ferrari Simona, Di Napoli Giulia, Guadagnolo Daniele, Sculco Eleonora, Albano Christian, Guercio Marika, Di Cecca Stefano, Milito Cinzia, Garzi Giulia, Pesce Anna Maria, Bonanni Livia, Sinibaldi Matilde, Bordoni Veronica, Di Cecilia Serena, Accordini Silvia, Castilletti Concetta, Agrati Chiara, Quintarelli Concetta, Zaffina Salvatore, Locatelli Franco, Carsetti Rita, Quinti Isabella

Abstract excerpt

Introduction: Assessing the response to vaccinations is one of the diagnostic criteria for Common Variable Immune Deficiencies (CVIDs). Vaccination against SARS-CoV-2 offered the unique opportunity to analyze the immune response to a novel antigen. We identify four CVIDs phenotype clusters by the integration of immune parameters after BTN162b2 boosters. Methods: We performed a longitudinal study on 47 CVIDs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37304298
DOI: 10.3389/fimmu.2023.1194225
PMCID: PMC10248522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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