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Article

Correlated decline of cognitive and motor phenotypes and ADRD pathologies in old age.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2023

Buchman Aron S, Wang Tianhao, Oveisgharan Shahram, Zammit Andrea R, Agrawal Sonal, Yu Lei, Bennett David A

Abstract excerpt

INTRODUCTION: Examining motor and cognitive decline in separate models may underestimate their associations. METHODS: In a single trivariate model, we examined the levels and rates of decline of three phenotypes, sensor-derived total daily physical activity, motor abilities, and cognition in 1007 older adults during 6 years of follow-up. In 477 decedents, we repeated the model adding fixed terms for indices of...

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Identifiers

PMID: 37303291
DOI: 10.1002/alz.13347
PMCID: PMC10524791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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