Article
Adult-onset Langerhans cell histiocytosis of bone: A case series highlighting a rare entity.
Annals of diagnostic pathology - 1 Oct 2023
Javadi Tiffany, Hill Charles, McLemore Morgan Lee, Oskouei Shervin, Bahrami Armita
Abstract excerpt
Langerhans cell histiocytosis (LCH) is a neoplastic disorder derived from LCH precursor cells that can manifest as a single-system disease or a multisystem disorder. While extensively studied in children, LCH has received less attention in adult patients. We aimed to investigate the pathology and clinical course of LCH in adults presenting with a bone lesion. Cases of osseous LCH diagnosed in patients ≥18 in our...
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