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MicroRNA ‐ 19a ‐ 3p Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence

18 Apr 2023

Abstract excerpt

ABSTRACT Aging is a major risk factor for most chronic diseases, including osteoporosis, and is characterized by an accumulation of senescent cells in various tissues. MicroRNAs (miRNAs) are critical regulators of bone aging and cellular senescence. Here, we report that miR ‐ 19a ‐ 3p decreases with age in bone samples from mice as well as in posterior iliac crest bone biopsies of younger versus older healthy...

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PMID: 37283656
DOI: 10.1002/jbm4.10745

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