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Article

Blood phytosterols in relation to cardiovascular diseases and mediating effects of blood lipids and hematological traits: a Mendelian randomization analysis.

Metabolism: clinical and experimental - 1 Sept 2023

Zhao Yimin, Zhuang Zhenhuang, Li Yueying, Xiao Wendi, Song Zimin, Huang Ninghao, Wang Wenxiu, Dong Xue, Jia Jinzhu, Huang Tao

Abstract excerpt

BACKGROUND: Short-term clinical trials have shown the cholesterol-lowering potentials of phytosterols, but their impacts on cardiovascular disease (CVD) remain controversial. This study used the Mendelian randomization (MR) to investigate the relationships between genetic predisposition to blood sitosterol concentration and 11 CVD endpoints, along with the potential mediating effects of blood lipids and...

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Source

Identifiers

PMID: 37270173
DOI: 10.1016/j.metabol.2023.155611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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