Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathway

1 Jun 2023

Abstract excerpt

Hepatic fibrosis is caused by liver damage as a consequence of wound healing response. Recent studies have shown that hepatic fibrosis could be effectively reversed, partly through regression of activated hepatic stellate cells (HSCs). Transcription factor 21 (TCF21), a member of the basic helix-loop-helix (bHLH) transcription factor, is involved in epithelial-mesenchymal transformation in various diseases....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics and Neurodevelopmental Disorders
Share to Liver Disease Diagnosis and Treatment
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37268177
DOI: 10.1016/j.phrs.2023.106808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNMT3a-mediated methylation of TCF21/hnRNPA1 aggravates hepatic fibrosis by regulating the NF-κB signaling pathwayPMID 37268177Read ↗

The roles of lncRNA in hepatic fibrosisSemantic proximity Read ↗

Microrna-21: A Central Regulator of Fibrotic Diseases Via Various TargetsSemantic proximity Read ↗

Role and mechanism of DNA methylation and its inhibitors in hepatic fibrosisSemantic proximity Read ↗

Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver FibrosisSemantic proximity Read ↗

Tripartite motif-containing protein 21 is involved in IFN-γ-induced suppression of hepatitis B virus by regulating hepatocyte nuclear factorsSemantic proximity Read ↗

Epigenetic Mechanisms in Hepatic Stellate Cell Activation During Liver Fibrosis and CarcinogenesisSemantic proximity Read ↗

Transcription factor 21 expression in injured podocytes of glomerular diseasesSemantic proximity Read ↗

Integration of miRNA‐regulatory networks in hepatic stellate cells identifies TIMP3 as a key factor in chronic liver diseaseSemantic proximity Read ↗

Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed ratsSemantic proximity Read ↗

Serum linc RNA ‐p21 as a potential biomarker of liver fibrosis in chronic hepatitis B patientsSemantic proximity Read ↗

DNA methyltransferase 1 knockdown reverses PTEN and VDR by mediating demethylation of promoter and protects against renal injuries in hepatitis B virus-associated glomerulonephritisSemantic proximity Read ↗

DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.