Article
Investigation of CRISPR-Independent Phage Resistance Mechanisms Reveals a Role for FtsH in Phage Adsorption to Streptococcus thermophilus.
Journal of bacteriology - 27 Jun 2023
Garrett Sandra C, Philippe Cecile, Kim Jenny G, Wei Yunzhou, Johnson Katie A, Olson Sara, Graveley Brenton R, Terns Michael P
Abstract excerpt
Prokaryotes are under constant pressure from phage infection and thus have evolved multiple means of defense or evasion. While CRISPR-Cas constitutes a robust immune system and appears to be the predominant means of survival for Streptococcus thermophilus when facing lytic phage infection, other forms of phage resistance coexist in this species. Here, we show that S. thermophilus strains with deleted CRISPR-Cas...
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