Article
Genetic Variants and Their Putative Effects on microRNA-Seed Sites: Characterization of the 3' Untranslated Region of Genes Associated with Temperament.
Genes - 28 Apr 2023
Ruiz-De-La-Cruz Gilberto, Sifuentes-Rincón Ana María, Casas Eduardo, Paredes-Sánchez Francisco Alejandro, Parra-Bracamonte Gaspar Manuel, Riley David G, Perry George A, Welsh Thomas H, Randel Ronald D
Abstract excerpt
The 3' untranslated region has an important role in gene regulation through microRNAs, and it has been estimated that microRNAs regulate up to 50% of coding genes in mammals. With the aim of allelic variant identification of 3' untranslated region microRNA seed sites, the 3' untranslated region was searched for seed sites of four temperament-associated genes (CACNG4, EXOC4, NRXN3, and SLC9A4). The microRNA seed...
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