Article
Single-nucleotide polymorphisms g.151435C>T and g.173057T>C in PRLR gene regulated by bta-miR-302a are associated with litter size in goats.
Theriogenology - 1 Jun 2015
An Xiaopeng, Hou Jinxing, Gao Teyang, Lei Yingnan, Li Guang, Song Yuxuan, Wang Jiangang, Cao Binyun
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) located at microRNA-binding sites (miR-SNPs) can affect the expression of genes. This study aimed to identify the miR-SNPs associated with litter size. Guanzhong (n = 321) and Boer (n = 191) goat breeds were used to detect SNPs in the caprine prolactin receptor (PRLR) gene by DNA sequencing, primer-introduced restriction analysis-polymerase chain reaction, and polymerase...
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