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Article

A Novel Longitudinal Phenotype-Genotype Association Study Based on Deep Feature Extraction and Hypergraph Models for Alzheimer's Disease.

Biomolecules - 23 Apr 2023

Kong Wei, Xu Yufang, Wang Shuaiqun, Wei Kai, Wen Gen, Yu Yaling, Zhu Yuemin

Abstract excerpt

Traditional image genetics primarily uses linear models to investigate the relationship between brain image data and genetic data for Alzheimer's disease (AD) and does not take into account the dynamic changes in brain phenotype and connectivity data across time between different brain areas. In this work, we proposed a novel method that combined Deep Subspace reconstruction with Hypergraph-Based...

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PMID: 37238598
DOI: 10.3390/biom13050728
PMCID: PMC10216733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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