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PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

23 May 2023

Abstract excerpt

Abstract Cardiac energy status, measured as phosphocreatine (PCr)/adenosine triphosphate (ATP) ratio with 31P-Magnetic Resonance Spectroscopy (31P-MRS) in vivo, is a prognostic factor in heart failure and is lowered in cardiometabolic disease. It has been suggested that, as oxidative phosphorylation is the major contributor to ATP synthesis, PCr/ATP ratio might be a reflection of cardiac mitochondrial function....

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PMID: 37221197
DOI: 10.1038/s41598-023-35041-7

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