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Article

Dissociated Oxygen Consumption and Carbon Dioxide Production in the Post-Cardiac Arrest Rat: A Novel Metabolic Phenotype.

Journal of the American Heart Association - 29 Jun 2018

Shinozaki Koichiro, Becker Lance B, Saeki Kota, Kim Junhwan, Yin Tai, Da Tong, Lampe Joshua W

Abstract excerpt

BACKGROUND: The concept that resuscitation from cardiac arrest (CA) results in a metabolic injury is broadly accepted, yet patients never receive this diagnosis. We sought to find evidence of metabolic injuries after CA by measuring O2 consumption and CO2 production (VCO2) in a rodent model. In addition, we tested the effect of inspired 100% O2 on the metabolism. METHODS AND RESULTS: Rats were anesthetized and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29959138
DOI: 10.1161/JAHA.117.007721
PMCID: PMC6064898

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