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Article

SOX2 Promotes Radioresistance in Non-small Cell Lung Cancer by Regulating Tumor Cells Dedifferentiation

1 Jan 2023

Abstract excerpt

Background: Radiation therapy plays an important role in the treatment of patients with non-small cell lung cancer (NSCLC).However, the radiocurability is greatly limited because of radioresistance which leads to treatment failure, tumor recurrence, and metastasis.Cancer stem cell (CSC) has been identified as the main factor that contributes to radiation resistance.SOX2, one of the transcription factors...

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PMID: 37213675
DOI: 10.7150/ijms.75315

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