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Article

TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c‐Myc

22 May 2023

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is one of the most common and lethal malignancies which including colon and rectum cancer. Tripartite motif containing 55 (TRIM55) is an E3 ubiquitin ligase belonging to the TRIM family. Although the aberrant TRIM55 expression has been implicated in several tumors, its functional role, and molecular mechanisms in CRC remain unknown. METHODS: Immunohistochemical studies,...

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PMID: 37212463
DOI: 10.1002/cam4.6020

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