Article
LncRNA BCLET variant confers bladder cancer susceptibility through alternative splicing of MSANTD2 exon 1.
Cancer medicine - 1 Jul 2023
Liu Hanting, Wang Xi, Guo Zheng, Sun Guanting, Lv Qiang, Qin Chao, Yuan Lin, Wang Yunyan, Du Mulong, Wang Meilin, Zhang Zhengdong, Chu Haiyan
Abstract excerpt
BACKGROUND: Alternative splicing (AS)-related single nucleotide polymorphisms (SNPs) are associated with risk of cancers, but the potential mechanism has not been fully elucidated. METHODS: Two-stage case-control studies comprising 1630 cases and 2504 controls were conducted to investigate the association between the AS-SNPs and bladder cancer susceptibility. A series of assays were used to evaluate the...
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