Article
LncRNA PVT1 accelerates malignant phenotypes of bladder cancer cells by modulating miR-194-5p/BCLAF1 axis as a ceRNA.
Aging - 16 Nov 2020
Chen Mingwei, Zhang Rongyuan, Lu Le, Du Jian, Chen Chunyang, Ding Keke, Wei Xuedong, Zhang Guangbo, Huang Yuhua, Hou Jianquan
Abstract excerpt
BACKGROUND: Numerous studies proved that long non-coding RNA (lncRNA) is involved in the progression of multifarious diseases, especially in some carcinomas. As a potential tumor biomarker, plasmacytoma variant translocation 1 gene (PVT1) is involved in the development and progression of multifarious cancers. Nevertheless, the intrinsic and concrete molecular mechanism of PVT1 in bladder cancer still remained...
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